Levels of Metrnβ production by BMM in response to various cytokines. TNFα induced the highest expression of Metrnβ in BMM, but IL-17α, IL-4, IL-1β, IL-5, and IL-12 also induced significant increases in Metrnβ levels. IFNγ and TGFβ reduced baseline production of Metrnβ by BMM. Bars represent mean+/− SEM. *p<0.05; **p<0.02; ***p<0.01; ****p<0.005. Results are representative of 3 experiments.