Skip to main content
. Author manuscript; available in PMC: 2019 Dec 15.
Published in final edited form as: J Immunol. 2018 Nov 21;201(12):3669–3676. doi: 10.4049/jimmunol.1800435

Figure 3. Metrnβ induces production of several cytokines and chemokines in macrophages.

Figure 3.

Induction of (A) IL-6 and (B) IL-10 in bone marrow macrophages (BMM) by Metrnβ as measured by ELISA. BMM were incubated in control medium or 100 ng/ml of Metrnβ for 24h and their supernatants were measured for IL-6 or IL-10 by ELISA. (C) Metrnβ induces expression of CXCL1 and CCL2 in peritoneal macrophages. Peritoneal cavity macrophages were incubated in the presence of Metrnβ (100 ng/ml) for 24 h prior to measuring levels of different cytokines and chemokines in supernatants using Legendplex (BioLegend). Bars represent the mean+/− SEM. **: p<0.02; ***: p<0.01. Results are representative of at least 3 experiments.