Fig 10. Thermodynamic cycle of the B₇ binding to AV and SAV.

(A) Enthalpy, (B) entropy, and (C) Gibbs free energy of the B₇ binding to AV (red) and SAV (green) for one transition state and no intermediate. The ΔH°_rxn, ΔS°_rxn, and ΔG°_rxn correspond to the average values found in multiple studies (Table 3). Arrhenius plots of the temperature dependent association and dissociation rate constants were used to calculate the E_a^forward and E_a^backwards, respectively.