Table 4. Linear regression results for disease phenotype, IBD genotype and additional clinical covariates (see Table 1) and the relative abundance of the C. coccoides-E. rectales bacterial subgroup and F. prausnitzii.

Log fold change was determined by real time qPCR. Variables with significant effects were bolded.

C. coccoides-E-rectales bacterial subgroup	Log fold change	p-value	FDR
Main effects
ileal CD	0.129	0.772	0.772
Colitis	1.456	0.002	0.004
Immunomodulators	-0.762	0.095	0.143
C. difficile fecal toxin	-1.08	0.290	0.347
First order interactions
Immunomodulators* C. difficile fecal toxin	4.71	0.001	0.004
Faecalibacterium prausnitzii	Log fold change	p-value	FDR
Main effects
ileal CD	-1.691	0.001	0.001
Colitis	-0.930	0.074	0.074