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. 2019 Feb 19;19(4):1–166.

Table 20:

Reference Case Analysis Results, Incremental Cost, Incremental Effectiveness, and Incremental Cost per Case Detected

Comparison Incremental Costs (95% CrI), $ Additional Cases Detected (95% CrI), n Difference in Diagnostic Tests (95% CrI), n Difference in Diagnostic-Procedure-Related Pregnancy Losses (95% CrI), n Difference in Affected Live Births (95% CrI), n Incremental Cost Per Case Detected, $
Second-tier NIPT vs. traditional prenatal screening −830,038 (−1,502,076 to –266,284) 30 (6–56) −2,392 (−3,275 to –1,612) −5 (−11 to 0) −11 (−34 to 12) Dominant
First-tier vs. second-tier NIPT 34,636,006 (27,131,648– 42,272,116) 84 (54–117) 1,407 (1,128–1,696) 3 (−1 to 7) −31 (−53 to –8) 411,274

Abbreviations: CrI, credible interval; NIPT, noninvasive prenatal testing.

Note: Numbers may appear inexact due to rounding.