Nova Scotia |
Yes |
Funded based on the following criteriaa:
Positive early combined screen of ≥ 1/50 (NT + early maternal serum testing)
Second-trimester positive screen (age, second-trimester maternal serum test, SIPS, or IPS) + genetic sonogram by maternal-fetal specialist and overall risk > 1/304)
People with a previous pregnancy with trisomy 21
|
Prince Edward Island |
Yes |
Nova Scotia provides medical genetics services to people from Prince Edward Island |
New Brunswick |
No |
None |
Newfoundland and Labrador |
No |
None |
Quebec |
Yes |
Announced funding for high-risk pregnant people in early 2018. Previously, Harmony, Panorama, or MaterniT21 PLUS were available at private clinics |
Ontario |
Yes |
Funded for people who meet one of the following criteria:
-
Category I
○ ≥ 40 years of age at time of delivery
○ Positive serum screen result
○ NT ≥ 3.5 mm
○ Previous pregnancy with a chromosome anomaly
-
Category II
○ Fetal congenital anomalies identified on ultrasound that are suggestive of trisomy 21, 18, or 13
○ Risk of aneuploidy for trisomies 21, 18, and 13 other than that of positive maternal multiple marker screen
○ < 40 years old at expected date of delivery (must have at least one other risk factor noted)
○ Risk of aneuploidy can be calculated by including any combination of risk indicators, including soft markers, biochemistry, maternal age, etc.
○ NIPT for sex chromosome determination for at least one of the following:
Risk of sex-limited disorder
Ultrasound findings suggestive of a sex chromosome aneuploidy
Ultrasound findings suggestive of a disorder of sex determination
Funding is available for NIPT analysis for trisomies 21, 18, and 13 and sex chromosome aneuploidies. Microdeletion testing is not funded |
Manitoba |
Yes |
Funded for people who meet one of the following criteriaa:
Either biological parent with a previous aneuploidy pregnancy (trisomy 21, 18, or 13)
Either biological parent is a carrier of a balanced Robertsonian translocation (involving chromosome 21 or 13)
Female carrier of a severe X-linked genetic disorder or has a child with a severe X-linked disorder for which prenatal detection would be considered (for fetal sexing)
Positive maternal serum screen for trisomy 21 or 18 in people who are HIV- or hepatitis-positive (surface-antigen-positive or E-antigenpositive) with detectable viral loads
Manitoba also serves some Ontario patients and counsels them according to Ontario criteria |
Saskatchewan |
No |
None |
Alberta |
No |
None |
British Columbia |
Yes |
Funded for people who meet one of the following criteria:
Positive screen result from IPS, SIPS, or quadruple screening
Previous trisomy 21, 18, or 13 pregnancy
Risk of Down syndrome > 1 in 300 based on results of screening and ultrasound marker(s) of aneuploidy
Funding is available for NIPT analysis for trisomies 21, 18, and 13, and sex chromosome aneuploidy. Microdeletion testing is not funded
The Harmony test is the only publicly funded test available for NIPT (i.e., Panorama is not publicly funded) |
Yukon |
Yes |
Funded for people who meet one of the following criteria:
People ≥ 35 years of age at estimated date of delivery
Positive screening result from SIPS, FTS, or quadruple screening
Serum screening + ultrasound markers risk ≥ 1/300
Ultrasound abnormality highly suggestive of trisomy 21, 18, or 13
Either biological parent had a previous pregnancy with aneuploidy
Personal or family history that increases the risk of trisomy 21, 18, or 13
Twin pregnancy
Carrier of X-linked condition in which gender identification is indicated
Positive for HIV, hepatits B, or hepatitis C
In vitro fertilization with intracytoplasmic sperm injection
|
Northwest Territories |
Yes |
A proposal to fund NIPT for pregnancies at increased risk of trisomy 21, 18, or 13 has been accepted |
Nunavut |
No |
Funded for people who meet one of the following criteria:
|