Table 4.
Genotypes and allele distributions in nonsmokers of healthy control (HC), aggressive periodontitis (AgP), and chronic periodontitis (CP) groups.
| Genotype | HC n = 97 (%) |
AgP n = 43 (%) |
CP n = 78 (%) |
χ2 | P |
|---|---|---|---|---|---|
| MMP-2-1306 | |||||
| CC | 88 (90.7) | 40 (93.0) | 68 (87.2) | 2.535 | 0.64 |
| CT | 9 (9.3) | 3 (7.0) | 9 (11.5) | ||
| TT | 0 (0.0) | 0 (0.0) | 1 (1.3) | ||
| C allele | 185 (95.4) | 83 (96.5) | 145 (92.9) | 1.691 | 0.43 |
| T allele | 9 (4.6) | 3 (3.5) | 11 (7.1) | ||
| MMP-2-735 | |||||
| CC | 45 (46.4) | 24 (55.8) | 40 (51.3) | 2.117 | 0.71 |
| CT | 41 (42.3) | 17 (39.5) | 31 (39.7) | ||
| TT | 11 (11.3) | 2 (4.7) | 7 (9.0) | ||
| C allele | 131 (67.5) | 65 (75.6) | 111 (71.2) | 1.920 | 0.38 |
| T allele | 63 (32.5) | 21 (24.4) | 45 (28.8) | ||
| MMP-2-790 | |||||
| TT | 81 (83.5) | 33 (76.7) | 58 (74.4) | 5.258 | 0.26 |
| GT | 16 (16.5) | 10 (23.3) | 18 (23.1) | ||
| GG | 0 (0.0) | 0 (0.0) | 2 (2.5) | ||
| T allele | 178 (91.8) | 76 (88.4) | 134 (85.9) | 3.068 | 0.22 |
| G allele | 16 (8.2) | 10 (11.6) | 22 (14.1) | ||
| TIMP-2-418 | |||||
| GG | 60 (61.9) | 29 (67.4) | 61 (78.2) | 11.270 | 0.024 |
| GC | 37 (38.1) | 13 (30.2) | 14 (17.9) | ||
| CC | 0 (0.0) | 1 (2.4) | 3 (3.9) | ||
| G allele | 156 (81.3) | 70 (83.3) | 136 (87.2) | 2.245 | 0.33 |
| C allele | 36 (18.7) | 14 (16.7) | 20 (12.8) | ||
| MMP-9-1562 | |||||
| CC | 77 (79.4) | 32 (74.4) | 57 (73.1) | 4.967 | 0.29 |
| CT | 18 (18.6) | 9 (20.9) | 21 (26.9) | ||
| TT | 2 (2.0) | 2 (4.7) | 0 (0.0) | ||
| C allele | 172 (88.7) | 73 (84.9) | 135 (86.5) | 0.842 | 0.66 |
| T allele | 22 (11.3) | 13 (15.1) | 21 (13.5) | ||
MMP = matrix metalloproteinase; TIMP, tissue inhibitor of MMPs.