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. 2017 Feb 11;12(1):83–90. doi: 10.1016/j.jds.2016.12.001

Figure 3.

Figure 3

IL-1β and MMP3 expression in the temporomandibular joint (TMJ) tissue after drug injection for 7 days. (A) Gene expression in the TMJ disc. IL-1β and MMP3 expression was higher in the CFA-induced arthritis group and CIA groups than in the control group and type I collagen groups. (B) Gene expression in the TMJ condyle. No significant difference was observed among the four groups. (C) Gene expression in the TMJ synovial tissue. IL-1β and MMP3 expression was higher in the CFA-induced arthritis and CIA groups than in the control and type I collagen groups. (* P < 0.05). CFA = complete Freund's adjuvant; CIA = collagen-induced arthritis.