Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
An example of information peptide-MHC binding and novel surface: Arg593Cys for HLA-DRB1*0101. (A) NetMHCII predicts there are binding tFVIII 15-mers that have two cores – IQRFLPNPA and YLTENIQRF – containing Arg593 (R593). (B) These two cores form pMHC surfaces that are novel compared to the equivalent surfaces for endogenous FVIII. FVIII: factor VIII; tFVIII: therapeutic factor VIII; MHC: major histocompatibility complex; pMHC: peptide-major histocompatibility complex.
