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. 2018 Oct 4;104(3):497–504. doi: 10.3324/haematol.2018.203158

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Figure 1. — Biological markers of dyserythropoiesis and correlation with response to erythropoiesis-stimulating agents. Response was defined according to the International Working Group 2006 criteria (IWG 2006) for hematologic improvement-erythroid. (A) Mean RED score before treatment for patients who did have a response (yes) or did not have a response (no). Non-responders had higher RED scores (P=0.01). (B) Mean hepcidin:ferritin ratio in patients who did or did not have a response; the hepcidin:ferritin ratio was lower in non-responders (P=0.04). (C) Mean GDF-15 level in patients who did or did not respond to erythropoietin-stimulating agent treatment (P=0.4).