Table 1.

Studies for the association of VDR genetic polymorphisms and susceptibility to periodontitis.

Locus	Subjects	Disease phenotype	Risks	Reference
ApaI BsmI FokI TaqI	Chinese	107 severe CP 121 HC	ApaI, BsmI & FokI: NS TaqI TT vs (Tt + tt) OR = 2.75  p = 0.02	Wang et al. (2009)
ApaI BsmI FokI TaqI	Chinese	51 GAgP 53 HC	ApaI, BsmI & TaqI: NS FokI FF vs (Ff + ff) OR = 2.90  p = 0.04	Li et al. (2008)
ApaI BsmI TaqI	Turkish	72 CP 102 HC	NS	Gunes et al. (2008)
ApaI BsmI FokI	Japanese	17 severe CP 80 not-severe CP	NS	Naito et al. (2007)
BsmI FokI TaqI	Korean	93 GAgP 143 HC	BsmI & TaqI: NS FokI FF vs (Ff + ff) OR = 1.83  p = 0.03	Park et al. (2006)
TaqI	Caucasian	51 AgP 57 CP 100 HC	AgP vs HC: NS CP vs HC TT vs (Tt + tt) OR = 2.7  p = 0.01	Brett et al. (2005)
BsmI TaqI	Brazilian	69 CP 44 HC	BsmI: NS TaqI (Tt + tt) vs TT OR = 2.4  p = 0.04	de Brito et al. (2004)
FokI TaqI	Japanese	74 CP 94 HC	FokI: NS TaqI TT vs Tt OR = 2.52  p = 0.03	Tachi et al. (2003)
TaqI	Japanese Chinese	72 AP, 94 HC 37 EOP, 39 HC	TT vs Tt OR = 2.44,  p = 0.04 Tt vs TT OR = 5.95  p = 0.02	Tachi et al. (2001)
TaqI	Chinese	24 AP, 37 EOP 39 HC	AP vs HC: NS EOP vs HC: Tt vs TT OR = 5.9  p = 0.02	Sun et al. (2002)
BsmI	Japanese	42 G-EOP 52 AP, 55 HC	NS	Yoshihara et al. (2001)
TaqI	Caucasian	49 G-EOP 20 L-EOP 72 HC	EOP vs HC: NS L-EOP vs HC tt vs (TT + Tt) OR = 8.99  p = 0.001	Hennig et al. (1999)

AgP: aggressive periodontitis; AP: adult periodontitis; CP: chronic periodontitis; EOP: early-onset periodontitis; L-EOP: localized early-onset periodontitis; G-EOP: generalized early-onset periodontitis; NS: no association.