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. 2019 Feb 22;12:24. doi: 10.3389/fnmol.2019.00024

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Copyright © 2019 Deng, Pushpitha, Joseph, Gupta, Rajput, Chitranshi, Dheer, Amirkhani, Kamath, Pascovici, Wu, Salekdeh, Haynes, Graham, Gupta and Mirzaei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Top 10 regulated proteins in four treatments. (B) Comparison of the top canonical pathways enriched from ingenuity pathway analysis (IPA) analysis of differentially regulated proteins (treatment vs. control) in four treatments. The significance of functional enrichment is highlighted with red color. (C) Functional interaction networks analyzed by the String Cytoscape plugin. One-hundred and one differentially expressed proteins were in pathways related to Alzheimer’s disease (AD). Network nodes are labeled with gene symbols.