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. 2019 Feb 22;10:129. doi: 10.3389/fneur.2019.00129

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Copyright © 2019 Kelbsch, Strasser, Chen, Feigl, Gamlin, Kardon, Peters, Roecklein, Steinhauer, Szabadi, Zele, Wilhelm and Wilhelm.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Post-Illumination Pupil Response (PIPR) metrics. Consensual pupillary response to 1 s pulses (horizontal blue line at time 0; 465 nm blue, 637 nm red-the gray line represents the pre- and post-stimulus periods in the dark) measured in Maxwellian view (35.6° diameter stimulus; 15.1 log quanta.cm⁻².s⁻¹). Details of the pupil light response (PLR) and Post-Illumination Pupil Response (PIPR) metrics are described in the figure. Data are for a representative healthy observer (traces are the average of 3 repeats). Traces courtesy of Prakash Adhikari, Beatrix Feigl and Andrew J. Zele.