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. 2019 Feb 22;9:53. doi: 10.3389/fonc.2019.00053

Figure 1.

Figure 1

Functional imaging in a SDHA-related metastatic PHEO/PGL. In this figure of a 33-year-old female patient (patient 8) demonstrating the superiority of 68Ga-DOTATATE PET/CT in comparison to other modalities, anterior maximum intensity projection (MIP) images of 68Ga-DOTATATE PET/CT (A), 18F-FDG PET/CT (B), 18F-FDOPA PET/CT (C), and anterior planar view whole body image of 123I-MIBG scintigraphy (D) scans demonstrate a large retroperitoneal tumor (arrows). The 68Ga-DOTATATE (A) and 18F-FDG PET/CT (B) scans show widespread metastases in bone and lymph nodes along with lesions in both lungs. The 68Ga-DOTATATE PET/CT scan detects more bone lesions than 18F-FDG PET/CT scan with a higher tumor uptake making the lesions on 68Ga-DOTATATE PET/CT scan relatively more conspicuous than 18F-FDG PET/CT scan. The duration between 68Ga-DOTATATE PET/CT scan and 18F-FDG PET/CT, 18F-FDOPA PET/CT, and 123I-MIBG scintigraphy were 1 day, 3 days, and 2 months, respectively.