Table 6.
Univariate and multivariate prediction of overall survival after TAE (Cox proportional hazards model). Variables with p<0.1 in the univariate model were included in the multivariate model. RR = relative risk of death.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| RR | P | RR | P | |
| < 100 μm particles used | 0.64 | 0.11 | ||
| Primary site | ||||
| Lung | 1.7 | 0.25 | ||
| Pancreas | 0.71 | 0.22 | ||
| Small bowel | 0.70 | 0.25 | ||
| Other or unknown | 1 | |||
| Degree of differentiation / grade | ||||
| Well differentiated, low grade | 0.71 | 0.20 | ||
| Well differentiated, intermediate to high grade; or moderately differentiated | 1.4 | 0.20 | ||
| Poorly differentiated or undifferentiated | 3.2 | 0.013 * | 5.0 | 0.0012 * |
| Unknown | 1 | |||
| Charlson comorbidity score (age adjusted) | 1.0 | 0.76 | ||
| Child Pugh score | 1.6 | 0.066 | 1.4 | 0.17 |
| ECOG performance status | 2.1 | 0.12 | ||
| Arteriovenous shunt on angiography | 3.6 | 0.030 * | 7.5 | 0.0079 * |
| Particle embolization of extrahepatic vessel at initial treatment | 0.85 | 0.75 | ||
| Extrahepatic metastases | 2.1 | 0.045 * | 1.4 | 0.44 |
| Disease volume ≥50% of liver | 3.1 | <0.001 * | 2.9 | <0.001 * |
| Degree of selectivity | ||||
| Lobar | 1 | |||
| Selective | 0.41 | 0.055 | 0.35 | 0.073 |
| Symptomatic or functional NET | 0.85 | 0.55 | ||
| Urgent inpatient treatment | 0.57 | 0.57 | ||