. Author manuscript; available in PMC: 2019 Apr 5.

Published in final edited form as: Mod Pathol. 2018 Oct 5;32(3):396–404. doi: 10.1038/s41379-018-0148-x

Table 4.

Effect of PTEN status on Tumor-Associated Immune Cell Infiltrates

Variable	Tumor PTEN Negative (59/132; 45%)	Tumor PTEN Positive/Heterogeneous (73/132; 55%)	p-value
CD3 (mean cells/mm², SD)
Overall	879 (556)	899 (575)	0.967
Hotspot	1466 (777)	1454 (868)	0.714
Periphery	908 (575)	900 (678)	0.517
Center	846 (588)	879 (562)	0.643
CD8 (mean cells/mm², SD)
Overall	462 (411)	495 (464)	0.969
Hotspot	781 (596)	803 (631)	0.998
Periphery	507 (472)	526 (500)	0.844
Center	413 (404)	464 (481)	0.912
CD68 (mean cells/mm², SD)
Overall	194 (159)	163 (119)	0.332
Hotspot	324 (232)	274 (196)	0.175
Periphery	182 (144)	156 (130)	0.219
Center	204 (182)	175 (137)	0.560