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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Curr Med Chem. 2019;26(33):6132–6148. doi: 10.2174/0929867325666180831150259

Figure 1. Exosomes biogenesis.

Figure 1.

Schematic representation of the origin and release of exosomes. Exosomes originate by the fusion of intracellular vesicles and early endosomes, heading to the origin of MVBs. MVBs can either fuse with lysosomes or with the membrane ending to the release of their content. There are other types of vesicles that are generated directly from the plasma membrane: microvesicles.