TABLE 4.

Viral and cellular binding partners of agnoprotein and associated functions

Polyomavirus names	Binding partners	Binding domain of agnoprotein	Associated functions	References
JCVPyV	JCV LT-Ag	1–36	Inhibition of JCV transcription and replication	Safak et al. (2001)
JCVPyV	JCV Sm t-Ag	ND	Inhibition of PP2A-mediated dephosphorylation of agnoprotein	Sariyer et al. (2008)
JCVPyV	JCV VP1	ND	Involved in virion assembly	Suzuki et al. (2012)
JCVPyV	HIV-1 Tat	18–54	Inhibition of Tat-mediated HIV promoter activation	Kaniowska et al. (2006)
JCVPyV	p53	1–36	Suppression of cell cycle progression	Darbinyan et al. (2002)
JCVPyV	Ku70	1–36	Inhibition of double-strand break repair	Darbinyan et al. (2004)
JCVPyV	PP2A	18–36	Dephosphorylation of agnoprotein	Sariyer et al. (2008)
JCVPyV	YB-1	1–36)	Inhibition of YB-1-mediated transcription of JCV promoters	Safak et al. (2002)
JCVPyV	FEZ1	ND	Inhibition of FEZ1-mediated neurite outgrowth	Suzuki et al. (2005)
JCVPyV	HP1α	1–18	Facilitation of nuclear export of JCV virions	Okada et al. (2005)
JCVPyV	AP-3	ND	Inhibition of PB-3-mediated vesicular trafficking	Suzuki et al. (2013)
BKPyV	α-SNAP	1–15	Inhibition of vesicle transport	Johannessen et al. (2011)
BKPyV	PCNA	1–15	Inhibition of DNA replication	Gerits et al. (2015)