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. Author manuscript; available in PMC: 2019 Mar 28.
Published in final edited form as: J Med Chem. 2019 Feb 13;62(4):1761–1780. doi: 10.1021/acs.jmedchem.8b01679

Figure 4.

Figure 4.

Inhibition of KOR Agonist Stimulated Prolactin Via p.o. Administration of 58a, b

a 58 was dosed as the monotartrate salt.

b 4 mice per dose group where 2 samples were collected per mouse.