Figure 7. Equivalent reduction in Gabra1 and Gria2 mRNA transcripts produce no net shift in excitatoryinhibitory balance following short-term unilateral deafness.
(A) Counts of Gria2 and Gabra1 transcripts in the ACtx contralateral to the deafened ear (dark purple hue) or in control mice (light purple hue). Each point represents the number of transcripts for a given cell. Squares indicate means of the Gria2 and Gabra1 distributions for each treatment group. (B) Cumulative distributions of Gria2 and Gabra1 transcripts in STUD and control mice. (C) The distribution of excitation/inhibition (E/I) index values from all cells in ACtx, according to the formula (Gria2 – Gabra1) / (Gria2 + Gabra1), where zero (dashed gray line) indicates an equivalent number of excitatory (Gria2) and inhibitory (Gabra1) transcripts. White squares represent the median of each distribution.