Table 2.
Comparison of neurological diseases/disorders and nervous system development functions between both sexes and males and females separately. NS = Not significant.
Disease or Function Annotation | P-values (number of genes) | ||
---|---|---|---|
Both Sexes | Males | Females | |
Autism or intellectual disability | 5.19E-04 (144) | 4.71E-16 (97) | 9.30E-10 (120) |
Mental retardation | 9.66E-04 (133) | 1.49E-14 (89) | 1.11E-09 (113) |
Familial syndromic intellectual disability | 6.51E-03 (84) | 1.40E-10 (58) | 3.09E-07 (73) |
Disorder of stature | 5.78E-03 (55) | 5.05E-03 (25) | 8.70E-06 (47) |
Autism | NS | 5.77E-03 (15) | NS |
Global developmental delay | NS | 4.40E-04 (4) | NS |
Developmental delay | 9.55E-04 (20) | NS | NS |
Development of central nervous system | NS | 4.06E-03 (21) | NS |
Development of neurons | NS | 5.14E-03 (21) | NS |
Morphogenesis of neurons | NS | 4.18E-04 (19) | NS |
Neuritogenesis | NS | 9.01E-04 (18) | NS |
Formation of brain | NS | 1.60E-03 (14) | NS |
Migration of neurons | NS | NS | 1.83E-05 (11) |