Table 2.
Comparison between the iNPH+/NTG+ and iNPH+/NTG− groups.
| Variables | non-NTG-iNPH | NTG-iNPH | p value‡ |
|---|---|---|---|
| ICP (mmHg) | |||
| Mean ± SD | 8.3 ± 1.4 | 10.8 ± 2.9 | †<0.005*** |
| [range] | 5.9–9.9 | 5.7–14.1 | |
| MMSE prior to CSF tapping | |||
| Mean ± SD | 22.33 ± 5.29 | 23.27 ± 4.73 | NS*** |
| [range] | 12–30 | 16–28 | |
| MMSE after CSF tapping | |||
| Mean ± SD | 24.22 ± 5.22 | 25.09 ± 4.09 | NS*** |
| [range] | 18–30 | 16–30 | |
| Cognitive function (improved: no improvement) (n) | 6:3 | 6:5 | NS*** |
| Gait disturbance (improved: no improvement) (n) | 8:1 | 6:5 | NS*** |
| P-tau | NS*** | ||
| Mean ± SD | 40.9 ± 12.7 | 51.8 ± 25.3 | |
| [range] | 27.8–63.2 | 32.3–109.0 | |
‡Two groups compared using the t-test.
†Statistically significant difference between the non-NTG-iNPH and NTG-iNPH groups (Steel-Dwass test).
SD, standard deviation; ICP, intra cranial pressure; MMSE, Mini-Mental State Examination; CSF, cerebrospinal fluid; p-tau, tau protein; NTG, normal-tension glaucoma: iNPH, idiopathic normal tension hydrocephalus.