Table 2.
Adipose-specific/enhanced genes associated with four categories of GWAS phenotypes.
| Gene | Region | Expression group | Specifically expressed tissue | Related trait category |
|---|---|---|---|---|
| SLC19A3 * | 2q36.3 | All 5 folds | Both | Obesity |
| LVRN (AQPEP)* | 5q23.1 | Subcutaneous fat | Blood Lipids | |
| LEP | 7q32.1 | Both | Type 2 diabetes | |
| FABP4 | 8q21.13 | Both | Obesity | |
| ITLN1 | 1q23.3 | Omental fat | Inflammation | |
| ALOX15 | 17p13.2 | Omental fat | Inflammation | |
| PPARG | 3p25.2 | 5 folds, except 1 | Both | Blood Lipids; Inflammation; Obesity; Type 2 diabetes |
| CD36 | 7q21.11 | Both | Blood Lipids | |
| CD300LG * | 17q21.31 | Both | Blood Lipids | |
| IL6 | 7p15.3 | Omental fat | Inflammation | |
| HAS1 * | 19q13.41 | Omental fat | Blood Lipids | |
| GPAM | 10q25.2 | 5 folds, except 2 | Both | Blood Lipids |
| ANGPTL4 | 19p13.2 | Subcutaneous fat | Blood Lipids | |
| UPK3B * | 7q11.23 | Omental fat | Obesity |
*Genes that have not been reported regarding their function in adipose tissue.