Table 4.
Univariate and multivariate analyses of disease-free survival in breast cancer patients.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| Age (years) | ||||
| <50 | 1 | 0.08 | ||
| ≥50 | 0.46 (0.19–1.09) | |||
| ER | ||||
| Negative | 1 | 0.29 | ||
| Positive | 0.65 (0.29–1.45) | |||
| Tumour size | ||||
| <20 mm | 1 | 0.00057 | 1 | 0.0014 |
| ≥20 mm | 4.14 (1.84–9.30) | 4.31 (1.76–10.53) | ||
| NG | ||||
| 1 | 1 | 0.029 | 1 | 0.17 |
| 2, 3 | 2.62 (1.10–6.25) | 1.93 (0.76–4.93) | ||
| HER2 | ||||
| Negative | 1 | 0.71 | ||
| Positive | 0.79 (0.24–2.65) | |||
| PgR | ||||
| Negative | 1 | 0.86 | ||
| Positive | 0.94 (0.43–2.03) | |||
| LN | ||||
| Negative | 1 | 0.09 | ||
| Positive | 1.97 (0.89–4.34) | |||
| PDW/P | ||||
| <0.59 | 1 | 1 | 0.37 | |
| ≥0.59 | 2.23 (1.02–4.85) | 0.044 | 1.56 (0.59–4.13) | |
| RDW | ||||
| <13.7 | 1 | 0.26 | ||
| ≥13.7 | 1.58 (0.72–3.50) | |||
| RPR | ||||
| <0.71 | 1 | 1 | 0.048 | |
| ≥0.71 | 2.21 (1.10–4.81) | 0.046 | 2.79 (1.01–7.69) | |
Abbreviations: NG, nuclear grade; LN, lymph node involvement; ER, oestrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2; PDW/P, platelet distribution width to platelet count ratio; RDW, red cell distribution width; RPR, red cell distribution width to platelet count ratio; CI, confidence interval.