Table 3.
Changes in blood cell counts.
| Group | PLT (× 109/L) | RET (× 109/L) | WBC (× 109/L) | RBC (× 1012/L) |
|---|---|---|---|---|
| Vehicle | 1234.3 ± 69.2 | 773.2 ± 41.9 | 6.5 ± 0.7 | 6.7 ± 0.1 |
| MCT | 57.4 ± 4.8∗∗∗ | 274.6 ± 16.3∗∗∗ | 1.6 ± 0.3∗∗∗ | 4.9 ± 0.2∗∗∗ |
| MCT + EPI (20 mg/kg) | 162.7 ± 89.4 | 366.4 ± 47.8## | 3.7 ± 1.1 | 5.3 ± 0.2 |
| MCT + EPI (40 mg/kg) | 1011.0 ± 140.5### | 510.3 ± 46.2## | 4.9 ± 0.6### | 6.9 ± 0.2### |
| EPI (40 mg/kg) | 1379.3 ± 78.4 | 691.7 ± 49.2 | 5.4 ± 0.8 | 7.3 ± 0.3 |
MCT: Monocrotaline, EPI: (-)epicatechin, PLT: platelet, RET: reticulocyte, WBC: white blood cell, RBC: red cell.
***P < 0.001 versus Vehicle control, ##P < 0.01, ###P < 0.001 versus MCT.