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Experimental scheme for the combination therapy experiment
| Drug regimen | No. of mice sacrificed at the following time pointsa
: |
|||||||
|---|---|---|---|---|---|---|---|---|
| D-38 | D-14 | D0 | W2 | W4 | W6 | W8 | Total | |
| Control | ||||||||
| Untreated | 5 | 5 | 5 | 5 | 20 | |||
| RIF10 | 5 | 5 | 5 | 5 | 20 | |||
| RIF10+STR150 | 5 | 5 | 5 | 5 | 20 | |||
| RIF10+CLR100 | 5 | 5 | 5 | 5 | 20 | |||
| Test | ||||||||
| RIF10+LZD50 | 5 | 5 | 5 | 5 | 20 | |||
| RIF10+LZD100 | 5 | 5 | 5 | 5 | 20 | |||
| RIF10+SZD50 | 5 | 5 | 5 | 5 | 20 | |||
| RIF10+TZD10 | 5 | 5 | 5 | 5 | 20 | |||
| Total | 5 | 5 | 5 | 35 | 40 | 35 | 35 | 160 |
W2, W4, W6, and W8 indicate completion of 2, 4, 6, and 8 weeks, respectively, of treatment.
