TABLE 1.
Species | Strain | MIC (mg/liter) |
Control growth (log10 CFU/lung) | Comment | |
---|---|---|---|---|---|
KBP-7072 | Minocycline | ||||
S. aureus | ATCC 33591 | 0.25 | 8 | 2.05 | MRSA |
ATCC 25923 | 0.25 | 0.125 | 1.80 | MSSA | |
ATCC 29213 | 0.25 | 0.06 | 1.62 | MSSA | |
MW2 | 0.25 | 2 | 1.60 | MRSA | |
R2527 | 0.25 | 2 | 2.55 | MRSA | |
S. pneumoniae | ATCC 10813 | 0.016 | 0.03 | 2.73 | Wild type |
1293 | 0.016 | 2 | 2.35 | Penr Tetr | |
1199 | 0.016 | 4 | 1.81 | Tetr | |
140 | 0.016 | 0.016 | 1.97 | Pens | |
673 | 0.008 | 0.004 | 1.62 | Penr | |
1285 | 0.016 | 0.03 | 2.01 | Peni |