TABLE 5.
Biocide cytotoxicity in an L929 murine fibroblast cell line
| Biocide | IC50a (mg/ml) |
Mol wt | Mean IC50b |
||
|---|---|---|---|---|---|
| NR | MTT | mg/ml | mmol/ml | ||
| PHMB | 0.02 | 0.03 | 2,800 | 0.026 | 0.000009 |
| Triclosan | 0.19 | 0.14 | 289.54 | 0.16 | 0.00057 |
| BAC | 0.07 | 0.03 | 340 | 0.047 | 0.00014 |
| Silver nitrate | 0.002 | 0.003 | 169.87 | 0.0027 | 0.000016 |
a
Mean concentration of biocides allowing 50% survival (IC50) of murine fibroblasts after 30 min at 37°C, as determined via NR and MTT assays.
b
Mean IC50 based on mass and molecular weight. Data indicate the results from two separate experiments each with six replicates.