TABLE 1.
Description of the cohort, demographics, comorbid conditions, and sources of infectiona
| Variable | Prevalence in the cohort (n = 61) |
|---|---|
| Age, yrs (mean ± SD) | 61 ± 18.4 |
| Sex (female) | 24 (39.3) |
| African-American race | 46 (75.6) |
| Residence in long-term care facility | 22 (36.1) |
| Comorbidities | |
| Lung disease | 25 (41.0) |
| Diabetes mellitus | 21 (34.4) |
| Chronic kidney disease | 19 (31.2) |
| Immunocompromise | 16 (26.2) |
| Congestive heart failure | 17 (27.9) |
| Cerebrovascular disease | 13 (21.7) |
| Coronary artery disease | 11 (18.0) |
| Dementia | 8 (13.1) |
| Malignancy | 6 (9.8) |
| Leukemia | 4 (6.6) |
| HSCT | 4 (6.6) |
| Lymphoma | 3 (4.9) |
| Charlson comorbidity index (median, IQR) | 5 (3, 7) |
| Median Pitt score when culture was collected (IQR) | 1 (0, 3) |
| Median SOFA score when culture was collected (IQR) | 4 (1, 6) |
| Epidemiologic categorization of infection | |
| Hospital acquired | 18 (29.5) |
| Health care facility acquired | 33 (54.1) |
| Community acquired | 10 (16.4) |
| Source of bloodstream infection | |
| Genitourinary | 19 (31.2) |
| Pulmonary | 16 (26.3) |
| Central venous catheter | 12 (19.7) |
| Intra-abdominal | 5 (8.2) |
| Skin and soft tissue | 3 (4.9) |
| Other | 2 (3.3) |
| Unknown | 4 (6.6) |
| Hospital location where blood culture was obtained | |
| General medicine | 33 (54.1) |
| Intensive care unit | 25 (41.0) |
| Emergency department | 3 (4.9) |
| Infectious diseases consult | 53 (86.9) |
| Pathogens | |
| E. coli, ESBL producing | 19 (31.1) |
| CRE | 15 (24.6) |
| P. aeruginosa | 13 (21.3) |
| K. pneumoniae, ESBL producing | 7 (11.4) |
| Acinetobacter spp. | 7 (11.4) |
a
Unless otherwise noted, data are presented as number (percent). HSCT, hematopoietic stem cell transplantation; ESBL, extended-spectrum beta-lactamase; CRE, carbapenem-resistant Enterobacteriaceae.