FIG 1.
Bacterial damage of biofilms of carbapenem-resistant K. pneumoniae bloodstream isolates caused by different concentrations of colistin (A), rifampin (B), meropenem (C), gentamicin (D), and tigecycline (E). The black column represents the MIC50 of each drug. Each concentration of each antibiotic was tested in pentaplicate per clinical isolate, and each drug-free control was tested in 16 replicates per experiment. All isolates were retested three times in independent experiments. The average values for these replicates were used in the data analysis to determine the mean ± standard error (SE) under each condition.