FIG 7.

ANY1 toxicity toward HK2 cells and peripheral blood mononuclear cells (PBMC). (a) HK2 cell viability following 24 h of exposure to 1 mg/ml FOM or various concentrations of ANY1 (0 to 224 μg/ml). Dimethyl sulfoxide ([DMSO] 10%) was used as a positive control for toxicity. *, P < 0.05, for comparison of results to those with the medium control. (b) PBMC viability following 24 h of exposure to 1 mg/ml FOM or various concentrations of ANY1 (0 to 224 μg/ml) and 112 μg/ml ANY1 in combination with different concentrations of FOM. Dimethyl sulfoxide (10%) was used as a positive control for toxicity. *, P < 0.05, for comparison of results to those with the medium control. All data presented in this figure are shown as the means ± standard deviations from at least three independent biological replicates.