TABLE 1.
Micafungin and anidulafungin MICs against the isolates from bottles spiked with the different tested inocula and proportions
|
Inoculum (CFU/ml) |
Proportion | EUCAST micafungin/anidulafungin MIC (mg/liter) for the following paira: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ||
| 1 × 103–5 × 103 | 9S/1R | 1/2 | 2/1 | 4/2 | 0.25/0.5 | 0.064/0.125 | 0.015/0.064 | 0.015/0.064 | 0.5/2 | 0.015/0.064 | 0.125/0.25 |
| 5S/5R | 2/2 | 2/1 | 4/2 | 0.25/0.5 | 0.064/0.25 | 1/2 | 1/1 | 1/2 | 0.5/1 | 4/2 | |
| 1S/9R | 1/2 | 1/0.5 | 4/2 | 0.5/1 | 0.064/0.25 | 1/1 | 1/2 | 1/2 | 0.5/1 | 4/2 | |
| 1 × 102–5 × 102 | 9S/1R | 1/0.5 | 0.064/0.125 | 2/2 | 0.25/0.5 | 0.064/0.125 | 0.015/0.064 | 0.015/0.064 | 0.5/1 | 0.015/0.064 | 0.25/0.25 |
| 5S/5R | 0.5/0.5 | 0.5/0.25 | 4/2 | 0.25/0.5 | 0.064/0.125 | 1/1 | 2/1 | 0.5/2 | 0.5/0.5 | 4/2 | |
| 1S/9R | 0.25/0.125 | 0.25/0.125 | 4/2 | 0.25/0.5 | 0.064/0.25 | 1/2 | 1/2 | 1/2 | 0.5/1 | 4/2 | |
| 10–50 | 9S/1R | 1/0.5 | 0.25/0.125 | 1/0.5 | 0.25/0.5 | 0.064/0.125 | 0.015/0.064 | 0.015/0.064 | 1/2 | 0.032/0.064 | 0.125/0.25 |
| 5S/5R | 1/0.5 | 0.5/0.125 | 1/0.5 | 0.25/0.5 | 0.064/0.125 | 1/0.5 | 0.5/0.25 | 1/2 | 0.5/0.5 | 4/2 | |
| 1S/9R | 2/1 | 2/1 | 4/2 | 0.5/0.5 | 0.064/0.25 | 1/2 | 2/1 | 0.5/2 | 0.5/0.5 | 4/2 | |
a
Bold numbers indicate EUCAST MICs showing echinocandin susceptibility for the tested isolates after preparing the inoculum from slime.