FIG 8.

Cytokines produced by host cells infected by RH tachyzoites with different stimuli. When infected by RH tachyzoites for 24h, mouse macrophages failed to produce significantly more TNF-α or less IL-10 than uninfected cells. Incubation of resveratrol with the infected cells could elevate the production of TNF-α but had no impact on IL-10 production in these cells. Meanwhile, pyrimethamine had an ignorable effect on the production of the two cytokines. −, uninfected by RH tachyzoites with or without reagents; +, infected by RH tachyzoites with reagents; RSV, resveratrol. The values shown are the means ± SEM from three independent experiments. *, P < 0.05.