Table I.
Basic information of 249 patients with refractory ITP [n (%)].
| Features | Rituximab group (n=79) | Cyclophosphamide group (n=86) | Combined therapy group (n=84) | χ2 test | P-value |
|---|---|---|---|---|---|
| Sex | 1.502 | 0.472 | |||
| Male | 26 (32.91) | 30 (34.88) | 35 (41.67) | ||
| Female | 53 (67.09) | 56 (65.12) | 49 (58.33) | ||
| Age (years) | 0.052 | 0.974 | |||
| <30 | 42 (53.16) | 47 (54.65) | 46 (54.76) | ||
| ≥30 | 37 (46.84) | 39 (45.35) | 38 (45.24) | ||
| Hematuria | 0.905 | 0.636 | |||
| Yes | 23 (29.11) | 31 (36.05) | 28 (33.33) | ||
| No | 56 (70.89) | 55 (63.95) | 56 (66.67) | ||
| Hematemesis or hemoptysis | |||||
| Yes | 31 (39.24) | 34 (39.53) | 35 (41.67) | 0.121 | 0.941 |
| No | 48 (60.76) | 52 (60.47) | 49 (58.33) | ||
| Epistaxis | 0.320 | 0.852 | |||
| Yes | 46 (58.23) | 50 (58.14) | 52 (61.90) | ||
| No | 33 (41.77) | 36 (41.86) | 32 (38.10) | ||
| Platelet count (×109/liter) | 3.307 | 0.508 | |||
| 20–50 | 24 (30.38) | 25 (29.07) | 30 (35.71) | ||
| >50 | 43 (54.43) | 40 (46.51) | 39 (46.43) | ||
| <20 | 12 (15.19) | 21 (24.42) | 15 (17.86) | ||
ITP, idiopathic thrombocytopenic purpura.