Table I.
Clinical characteristics of the study population.
| Parameter | CO (n=20) | SG0 (n=19) | RYGB0 (n=7) | SG3 (n=8) | RYGB3 (n=3) | P<0.05 comparisons |
|---|---|---|---|---|---|---|
| Age (years) | 31.5±10.3 | 32.9±7.1 | 45.7±9.4 | 33.3±6.5 | 40.3±6.8 | CO vs. RYGB0; SG0 vs. RYGB0; |
| Females | 14 (70%) | 16 (84%) | 4 (57%) | 8 (100%) | 3 (100%) | |
| T2DM | 14 (74%) | 7 (100%) | 0 (0%) | 2 (67%) | SG0 vs. SG3 | |
| BMI (kg/m2) | 22.4±1.4 | 41±5.6 | 30±4.7 | 30.6±3.8 | 26.2±2 | CO vs. SG0; CO vs. RYGB0; |
| SG0 vs. SG3 | ||||||
| GHb (%) | 7.4±2 | 7.8±1.6 | 5.6±0.4 | 7.4±1.4 | SG0 vs. SG3; | |
| Glu (mmol/l) | 5.7±2.2 | 7.4±3.4 | 4.9±0.9 | 9.3±2.3 |
As the healthy volunteers refused invasive testing, T2DM, GHb and Glu for the CO group were not provided. In the SG0 group, 14 out of 19 patients had T2DM. At 3 months after SG, only 8 patients were available for follow-up, 4 of which had pre-operative T2DM, and all of them achieved complete T2DM remission (complete remission rate, 100%). In the RYGB0 group, 7 patients had T2DM. At 3 months after RYGB, only 3 patients were available for follow-up and of these, 1 achieved complete T2DM remission, while the other 2 patients achieved partial T2DM remission (complete remission rate, 33%). T2DM, type 2 diabetes mellitus; BMI, body mass index; GHb, glycosylated haemoglobin; Glu, blood glucose; BMI, body mass index; CO, control group; SG, sleeve gastrectomy; RYGB, Roux-en-Y gastric bypass; SG0/3, group prior to/3 months after SG.