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Structure of miR-212. (A) Using the miRBase database, the miR-212 precursor (upper) and mature (lower) structures were identified. (B) The GC box and the TATA box were located at the transcription initiation point of miR-212 and there were 5 HERs (5′-A/GCGTG-3′) identified. miR, microRNA; HER, hypoxia response element; ChIP, chromatin immunoprecipitation assay.
