Fig. 3.

Diffuse gliomas with low GluCEST contrast.

FLAIR and T₁ weighted images coregistered with GluCEST sequences revealing low tumour GluCEST contrast. (A–D) 37 year-old, seizure-free man with WHO grade II diffuse astrocytoma IDH-mutant (patient 3). No adjuvant therapy prior to 7 T MRI. (E–H) 30 year-old gentleman with tumour associated epilepsy, WHO grade II Diffuse astrocytoma IDH-mutant (patient 8). No adjuvant therapy prior to 7 T MRI. (A/E) = 3 T axial FLAIR (tumour identified by white arrows); (B/F) = 7 T axial T1 weighted imaging (tumour identified by white arrows); (C/G) = GluCEST contrast map (tumour identified by black arrows); (D) = Co-registered T1 and GluCEST (tumour identified by arrow heads); (H) = Co-registered FLAIR and GluCEST (tumour identified by arrow heads).