Fig. 4.

Tumours with heterogenous increased GluCEST contrast.

FLAIR and T₁ weighted images coregistered with GluCEST sequences revealing heterogenous increased tumour GluCEST contrast. (A–D) 33 year-old male, oligodendroglioma IDH-mutant, 1p/19q co-deleted at diagnosis, radiological progression of tumour and treatment with chemoradiotherapy prior to 7 T MRI (patient 4). (E–H) 55 year-old woman, oligodendroglioma IDH-mutant, 1p/19q co-deleted at diagnosis, radiological progression and treatment with chemotherapy prior to 7 T MRI (patient 7). (A) = 3 T axial FLAIR (tumour identified by white arrows); (E) = 7 T axial FLAIR (tumour identified by white arrows; (B/F) = 7 T axial T1 weighted imaging (tumour identified by white arrows); (C/G) = GluCEST contrast map (tumour identified by black arrows); (D/H) = Co-registered T1 and GluCEST (tumour identified by arrow heads).