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. 2019 Jan 17;40(9):768–784. doi: 10.1093/eurheartj/ehy881

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© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Effects of treatment with cyclophosphamide and mycophenolate mofetil in patients with autoantibodies to neutrophil cytoplasmic antigens vasculitis. (A and B) Systolic and diastolic blood pressure, with two-way analysis of variance showing a significant effect of treatment (P = 0.001). (C and D) The relationship between change in circulating monocyte count and changes in systolic and diastolic blood pressure is shown. (E) Plasma endothelin-1 (effect of treatment P = 0.0225) and (F) urine endothelin-1 (effect of treatment P = 0.2053). (G and H) Monocyte expression of endothelin-A (P = 0.1310) and endothelin-B receptors (P = 0.0001) in patients with autoantibodies to neutrophil cytoplasmic antigens vasculitis, compared by one-way analysis of variance with adjusted P-values are shown.