. 2019 Feb 28;5:70–80. doi: 10.1016/j.trci.2019.01.003

Table 1.

Genotype effects on sleep

Sleep parameter	Genotype	Least-squared mean (95% confidence interval)	Test statistic (degrees of freedom)	P value	Average % change, 5XFAD versus WT
Sleep percent
Light phase sleep	5XFAD	59.7 (58.3, 61.1)	t(89) = −2.23	.029	−3.4
	WT	61.8 (60.6, 63.2)	t(89) = −2.23	.029	−3.4
Dark phase sleep	5XFAD	24.2 (22.2, 26.3)	t(89) = −2.60	.011	−13.6
	WT	28.0 (25.9, 31.1)	t(89) = −2.60	.011	−13.6
Total 24-h sleep	5XFAD	42.9 (41.7, 44.2)	t(87) = −3.13	.002	−6.0
	WT	45.6 (44.4, 46.8)	t(87) = −3.13	.002	−6.0
Bout length (s)
Light phase bouts	5XFAD	61.3 (58.1, 64.4)	t(89) = −2.40	.018	−8.0
	WT	66.6 (63.4, 69.7)	t(89) = −2.40	.018	−8.0
Dark phase bouts	5XFAD	33.8 (30.5, 37.2)	t(87) = −2.41	.018	−14.4
	WT	39.5 (36.2, 42.8)	t(87) = −2.41	.018	−14.4
Total 24-h bouts	5XFAD	49.7 (46.9, 52.5)	t(87) = −2.05	.043	−7.6
	WT	53.8 (51.0, 56.7)	t(87) = −2.05	.043	−7.6

Abbreviation: WT, wild type.