Figure 4.

Bioinformatics analysis for circLPAR1 in muscle-invasive bladder cancer. Top 15 (A) Gene Ontology-Analysis-BP items and (B) Kyoto Encyclopedia of Genes and Genomes pathways for circLPAR1. (C) The negative regulation between circLPAR1 and miRNAs. (D) circLPAR1 may harbor four miRNAs according to the miRNA seed sequence matching. (E) A schematic drawing illustrated the putative binding sites of the four miRNAs. (F) The two most markedly enriched GO-items for the four matched miRNAs. miRNAs, microRNAs; circLPAR1, circular lysophosphatidic acid receptor 1.