Table 4.
Fecal metabolites of cholestyramine-supplemented dogs
| Treatment | ||||
|---|---|---|---|---|
| CON | CHOL | |||
| --- μmol/g DM basis --- | SEM | P-value | ||
| Total SCFA1 | 414.08 | 704.95 | 86.73 | 0.001 |
| Acetate | 229.91 | 434.48 | 52.41 | <0.001 |
| Butyrate | 62.21 | 101.29 | 14.69 | 0.004 |
| Propionate | 121.96 | 169.18 | 22.04 | 0.145 |
| Total BCFA1 | 31.60 | 34.75 | 4.23 | 0.632 |
| Isobutyrate | 11.31 | 13.36 | 1.59 | 0.479 |
| Isovalerate | 18.34 | 19.78 | 2.60 | 0.933 |
| Valerate | 1.94 | 1.60 | 0.53 | 0.250 |
| Total indoles + phenols | 4.61 | 4.66 | 0.49 | 0.945 |
| Indoles | 3.14 | 4.20 | 0.34 | 0.039 |
| Phenols | 1.47 | 0.45 | 0.31 | 0.047 |
| Ammonia | 304.54 | 230.12 | 37.50 | 0.019 |
n = 12 per group.
1Total short-chain fatty acids (SCFA) = acetate + butyrate + propionate; total branched-chain fatty acids (BCFA) = valerate + isovalerate + isobutyrate.