Fig. 12.
Structure of the 2′-deoxy non-obligate chain terminator Entecavir that features a unique exocyclic double bond which leads to unfavorable steric interactions resulting in chain termination despite the presence of a 3′-OH.
Structure of the 2′-deoxy non-obligate chain terminator Entecavir that features a unique exocyclic double bond which leads to unfavorable steric interactions resulting in chain termination despite the presence of a 3′-OH.