Figure 1.

(A) SEM and (B) TEM image of SQU@PCN. (C) Hydrodynamic size and PDI of SQU@PCN during 7 days of soaking in water. (D) PXRD patterns of SQU@PCN after treatment with or without ATP at different times. (E) Release of SQU from SQU@PCN in different HEPES buffer solutions. (F) Detailed process of SQU@PCN-mediated chloride transport. (a) ATP-responsive SQU release from SQU@PCN. (b) Chloride transport of released SQU in POPC vesicle. (c) Chloride transport mechanism of released SQU by mobile carrier and ion exchange. (G) Chloride efflux after treatment with different samples at different times. (H) Chloride efflux mediated by SQU@PCN after treatment with or without ATP at different times. (I) ROS production of different samples in the solution containing ATP.