Figure 6.
(A) Main hematological and biochemical parameters of mice after treatment with PBS, SQU@PCN, and SQU. Concentration of (B) ALT and (C) AST in blood of mice after treatment with PBS, SQU@PCN, and SQU. **P < 0.01. (D) Fluorescence imaging in vivo after intravenous injection with SQU@PCN and ex vivo tissues after 36 h postinjection. Ki, kidney; Li, liver; Tu, tumor; Lu, lung; He, heart; and Sp, spleen. (E) Detailed operation process of antitumor treatment against HeLa tumor-bearing mice with SQU@PCN in vivo. (F) Relative body weight and (G) relative tumor volume of mice during 14 days of treatment. (H) Photographs and (I) weight of tumor tissues ex vivo obtained on the 14th day. Scale bar: 1 cm. ***P < 0.001. “hv” refers to light irradiation with a 660 nm laser at 220 mW/cm2 for 8 min.