Table 2.

Genetic variants of HOTAIR and PC risk in Stage 1

Genotype	Cases	Controls	Crude OR (95% CI)	Adjusted OR (95% CI)a
rs4759314
AA	327	354	1.00 (reference)	1.00 (reference)
AG	65	44	1.60 (1.06–2.41)	1.66 (1.09–2.54)
GG	8	2	4.33 (1.04–18.1)	4.50 (1.11–18.3)
G vs A			1.76 (1.22–2.55)	1.84 (1.26–2.67)
P trend			0.024	0.018
rs12427129
GG	359	356	1.00 (reference)	1.00 (reference)
AG	36	41	0.87 (0.54–1.39)	0.91 (0.66–1.25)
AA	5	3	1.65 (0.4–6.87)	1.72 (0.4–7.43)
A vs G			0.98 (0.64–1.49)	1.02 (0.76–1.35)
P trend			0.564	0.546
rs200349340
GG	205	236	1.00 (reference)	1.00 (reference)
TG	161	140	1.32 (0.99–1.78)	1.38 (1.00–1.89)
TT	34	24	1.63 (0.94–2.83)	1.70 (0.96–2.99)
T vs G			1.31 (1.04–1.63)	1.36 (1.06–1.73)
P trend			0.061	0.014
rs12312094
CC	260	278	1.00 (reference)	1.00 (reference)
CG	128	116	1.18 (0.87–1.6)	1.18 (0.87–1.60)
GG	12	6	2.14 (0.81–5.66)	2.13 (0.81–5.65)
G vs C			1.23 (0.95–1.59)	1.23 (0.89–1.70)
P trend			0.284	0.214
rs1838169
CC	269	275	1.00 (reference)	1.00 (reference)
CG	122	118	1.06 (0.78–1.43)	1.10 (0.67–1.80)
GG	9	7	1.31 (0.48–3.57)	1.37 (0.46–4.06)
G vs C			1.07 (0.83–1.39)	1.12 (0.76–1.64)
P trend			0.721	0.577
rs7958904
GG	215	237	1.00 (reference)	1.00 (reference)
CG	156	136	1.26 (0.94–1.7)	1.31 (0.94–1.82)
CC	29	27	1.18 (0.68–2.06)	1.23 (0.64–2.36)
C vs G			1.17 (0.94–1.47)	1.22 (0.93–1.59)
P trend			0.119	0.147

^aAdjusting for age, gender, diabetes, drinking and smoking

Italic values indicate significant of p value (P<0.05)