Table II.
Summary of various reported Indian studies
A. Clinical parameters of 28 narcolepsy patients | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Author | Type of study | Frequency (%) | Age onset (yr) | BMI (kg/m2) | Type | EDS | Cataplexy (%) | Hypnagogic hallucinations (%) | Sleep paralysis (%) | Sleep attacks | |||
Gupta et al4 (n=20) | Observational | 20/1024 (1.9) | 25±10 | 26±4 | Idiopathic | All | 12/20 (60) | 8/20 (40) | 12/20 (60) | All | |||
Bhatia and Arif5 (n=1) | Case report | NA | NA | 26.5 | Idiopathic | Yes | Yes | No | No | Yes | |||
Shehna et al6 (n=1) | Case report | NA | 30 | NA | NA | Yes | Yes | Yes | Yes | Yes | |||
Gupta et al7 (n=1) | Case report | NA | 35 | 26 | Idiopathic | Yes | Yes | Yes | Yes | Yes | |||
Panda 20148 (n=1) | Case report | NA | 56 | 28.6 | Idiopathic | Yes | Yes | Yes | No | Yes | |||
Present study (n=4) | Case series | 4/1175 (0.3) | 26.2±6.4 | 24.2±4.7 | Idiopathic | All | 1/4 (25) | 1/4 (25) | 1/4 (25) | All | |||
B. Polysomnography and multiple sleep latency test parameters of 28 narcolepsy patients | |||||||||||||
Author | Sleep duration (min) | Sleep efficiency (%) | REM sleep (%) | RDI (events/h) | Arousal index (events/h) | Sleep latency (min) | eREM latency (min) | ||||||
Gupta et al4 (n=20) | 421±85.8 | 79.4±12.4 | 36.7±3.5 | 0.4±1.1 | 18.7±10.3 | 1.3±0.3 | 2.5±0.6 | ||||||
Bhatia and Arif5 (n=1) | NA | NA | NA | Normal | NA | 0.46 | Short | ||||||
Shehna et al6 (n=1) | NA | NA | NA | NA | NA | 0.25 | 5 | ||||||
Gupta et al7 (n=1) | 310 | 96 | Normal | 2 | NA | 0.7 | 8 | ||||||
Panda8 (n=1) | NA | 94.9 | 27.9 | Normal | NA | 1.4 | Short | ||||||
Present study (n=4) | 461.7±47.5 | 92±4.9 | 17.8±5.2 | 0.8±1.05 | 38.5 (14.5-61.9)* | 2.7±1.3 | 5.7±2.9 |
Data expressed as mean±SD; *Data expressed in median (interquartile range). EDS, excessive daytime sleepiness; REM, rapid eye movement; RDI, respiratory distress index; NA, not available; SD, standard deviation; BMI, body mass index