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. 2019 Feb 26;13:767–774. doi: 10.2147/DDDT.S179101

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© 2019 Guo et al. This work is published and licensed by Dove Medical Press Limited

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GB inhibits ER stress induced by I/R. Sprague Dawley rats were divided into Sham, Sham+GB, I/R, and I/R+GB groups as mentioned above. (A, B) Relative protein expression was detected by Western blot. (C) Apoptosis was measured by TUNEL assay. (D) Apoptosis index. The bars shows means±SD of three independent experiments. ^aP <0.5 compared with Sham group; ^bP <0.05 compared with I/R group.

Abbreviations: ER, endoplasmic reticulum; GB, ginkgolide B; I/R, ischemia reperfusion; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling.