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. 2019 Feb 12;12:29. doi: 10.3389/fnmol.2019.00029

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Copyright © 2019 Maj, Wagner and Tretter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sites of secretagogin action in secreting cells. Secretagogin action in secreting cells (insulin secreting pancreatic beta cells, stress hormone releasing neurons or other SCGN⁺ neurons) is manifold according to protein interaction partners identified by proteomic studies. Some of these processes have been investigated into detail (see main text for details), while the relevance of many other protein interactions are still unexplored. Abbreviations: MAP, microtubule-associated protein; SNARE, soluble N-ethylmaleimide-sensitive-factor attachment receptor; PLC, phospholipase C; MAPK, mitogen-activated protein kinase; Arp, actin-related protein; USP, ubiquitin-specific-processing protease.