Table 2.
T-test and one-way ANOVA were used to test differences between groups.
| T-test (HC vs. MS) | ANOVA F (HC vs. CIMS vs. CPMS) | ANOVA post hoc | T-test (CIMS vs. CPMS) | T-test (HC vs. CIMS, HC vs. CPMS) | |
|---|---|---|---|---|---|
| Age | ∗∗ | F(2,83) = 7.90 ∗∗ | ∗∗a,b | / | / |
| Disease duration | / | / | / | ∗ | / |
| Median EDSS | / | / | / | ∗∗ | / |
| SDMT | ∗∗ | / | / | / |
∗∗ (HC-CI) ∗∗ (HC-CP) |
| HADS-A | n.s. | F(2,83) = 0.76 n.s. | n.s. | / | / |
| HADS-D | ∗∗ | F(2,83) = 6.04 ∗∗ | ∗b ∗∗a |
/ | / |
| NART-predict | n.s. | F(2,83) = 2.46 n.s. | ∗c | / | / |
| BPF | ∗∗ | F(2,82) = 9.93 ∗∗ | ∗c ∗∗a,b |
/ | / |
| WM-LL | / | / | / | n.s. | / |
| WM-FA | ∗∗ | F(2,83) = 216.03 ∗∗ | ∗∗a,b | / | / |
| GE(CBL-DMN) | ∗∗ | F(2,83) = 27.53 ∗∗ | ∗∗a,b | / | / |
| GE(DMN) | ∗∗ | F(2,83) = 37.79 ∗∗ | ∗∗a,b | / | / |
| GE(CBL) | ∗∗ | F(2,83) = 10.53 ∗∗ | ∗b ∗∗a |
/ | / |
A T-test was first run between HC and MS and results are reported in the first column (∗∗p < 0.01, ∗p < 0.05, n.s.: not significant). One-way ANOVA was used to test differences between HC, CIMS, and CPMS. F- and p-values are reported in the second column, while the third column reports results obtained from ANOVA post hoc tests (LSD) between pairs of groups (within this column only significant findings are reported). The ANOVA was not run to test differences of SDMT scores between CIMS and CPMS that were defined on the basis of SDMT itself or for disease-related measures that were not performed in HC; T-tests were, instead, run for the relevant group pairs. The fourth column reports results for CIMS-CPMS comparisons of disease-related measures. The last column shows significant differences in SDMT scores between HC and CIMS and between HC and CPMS resulting from T-tests. aSignificant difference between HC and CIMS; bSignificant difference between HC and CPMS; cSignificant difference between CIMS and CPMS.